Which condition is characterized by excessive gastrin production leading to recurrent peptic ulcers?

The condition characterized by excessive gastrin production leading to recurrent peptic ulcers is Zollinger-Ellison syndrome. In this syndrome, one or more gastrin-secreting tumors, known as gastrinomas, are typically found in the pancreas or duodenum. These tumors produce high levels of gastrin, which stimulates the gastric mucosa to secrete excessive amounts of gastric acid. The elevated acid levels can lead to the formation of recurrent peptic ulcers in the stomach and the duodenum.

Patients with Zollinger-Ellison syndrome often present with symptoms that include abdominal pain, diarrhea, and complications from ulcer disease, making the association between gastrin production and peptic ulcers a hallmark of this condition. The diagnosis may involve measuring serum gastrin levels and imaging studies to localize gastrinomas.

In contrast, other conditions mentioned do not have the same pathophysiological mechanism of gastrin overproduction leading to recurrent ulcers. Biliary reflux involves the backflow of bile into the stomach and does not elevate gastrin levels. Eosinophilic gastroenteritis is primarily an allergic or inflammatory condition of the gastrointestinal tract, while celiac disease is an autoimmune disorder that leads to gluten-induced injury in the small intestine, neither of which is